Leqembi, other new Alzheimer’s drugs require better biomarkers

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David Liu- Broad Retreat
David Liu proposed prime editing of genes in 2019. The technology has passed a big test. Courtesy ErikJacobs/Broad Institute

Prime Medicine said Friday it successfully used a new, ultra-versatile form of genetic surgery called prime editing to edit liver cells in monkeys.

The results, presented at the European Society of Gene & Cell Therapy meeting in Brussels, are a major step for a technology that could transform treatment of numerous diseases.

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“I think the big celebration here is we’re showing, in primates, for the company, that we have a delivery system that is working and is safe,” said Jeremy Duffield, Prime’s chief scientific officer.

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